\begin{abstract} Recent full hydrodynamic simulations of a sonoluminescing bubble interior have shown that the bubble content is compressed to a very dense state during the violent collapse. In this paper, we numerically studied the shape stability of a radially oscillating gas bubble by using Hilgenfeldt {\it et al.} theoretical model with corrections taking into account the gas density effect. Our results show that gas density variations not only significantly suppress the Rayleigh-Taylor instability, but also enhance the threshold of the parametric instability under sonoluminescence conditions. \end{abstract}